Engineering an artificial alveolar-capillary membrane: a novel continuously perfused model within microchannels

Artificial Alveolar-Capillary Membrane on a Microchip

Albuterol Improves Alveolar-Capillary Membrane Conductance in Healthy Humans

BACKGROUND Beta-2 adrenergic receptors (β2ARs) are located throughout the body including airway and alveolar cells. The β2ARs regulate lung fluid clearance through a variety of mechanisms including ion transport on alveolar cells and relaxation of the pulmonary lymphatics. We examined the effect of an inhaled β2-agonist (albuterol) on alveolar-capillary membrane conductance (DM) and pulmonary c...

The alveolar-capillary membrane diffusing capacity and the pulmonary capillary blood volume in heart transplant candidates.

OBJECTIVES To determine the mechanism of impairment of pulmonary transfer factor for carbon monoxide (TL(CO)) in heart transplant candidates, as this is the most common lung function abnormality. SETTING Regional cardiopulmonary transplant centre. METHODS TL(CO) and its components (the diffusing capacity of the alveolar-capillary membrane (D(M)) and the pulmonary capillary blood volume (V(C...

The alveolar-capillary membrane diVusing capacity and the pulmonary capillary blood volume in heart transplant candidates

Objectives—To determine the mechanism of impairment of pulmonary transfer factor for carbon monoxide (TLCO) in heart transplant candidates, as this is the most common lung function abnormality. Setting—Regional cardiopulmonary transplant centre. Methods—TLCO and its components (the diVusing capacity of the alveolar-capillary membrane (DM) and the pulmonary capillary blood volume (VC)) were meas...

Membrane Engineering: Future Perspectives